Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/66798
Title: Simple structure model for enzyme production by Phanerochaete chrysosporium
Authors: Zheng, Z.
Foo, Y.D.
Obbard, J.P. 
Lin, J.
Cen, P.
Keywords: Lignin peroxidase (LiP)
Manganese peroxidase (MnP)
Model simulation
mRNA
Repressor
Secondary metabolite
White rot fungi
Issue Date: Aug-2003
Source: Zheng, Z.,Foo, Y.D.,Obbard, J.P.,Lin, J.,Cen, P. (2003-08). Simple structure model for enzyme production by Phanerochaete chrysosporium. Chinese Journal of Chemical Engineering 11 (4) : 414-419. ScholarBank@NUS Repository.
Abstract: In order to understand the behavior of ligninolytic enzyme production by white rot fungi Phanerochaete chrysosporium, study on time courses and a mathematical model for the production of lignin peroxidase (LiP) and manganese peroxidase (MnP) of the fungi was undertaken. Based on the Monod-Jacob operon model, the ligninolytic enzyme would be synthesized in the absence of a related repressor. The repressor is assumed to be active in the presence of ammonia nitrogen, and as combined as co-repressor, it causes the inhibition of enzyme synthesis. The model can explain the mechanism of extracellular ligninolytic enzyme production by white rot fungi. The results, as predicted by the model, correspond closely to those observed in experimental studies. In addition, some light is also shed on unmeasured variables, such as the concentrations of repressor and mRNA that are related to the enzyme synthesis.
Source Title: Chinese Journal of Chemical Engineering
URI: http://scholarbank.nus.edu.sg/handle/10635/66798
ISSN: 10049541
Appears in Collections:Staff Publications

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