Please use this identifier to cite or link to this item: https://doi.org/10.1002/1097-4636(20010905)56:3<324
Title: Modification of Si(100) surface by the grafting of poly(ethylene glycol) for reduction in protein adsorption and platelet adhesion
Authors: Zhang, F.
Kang, E.T. 
Neoh, K.G. 
Wang, P. 
Tan, K.L. 
Keywords: Grafting
Plasma
Platelet adhesion
Poly(ethylene glycol) methacrylate (PEGMA)
Protein adsorption
Si(100)
X-ray photoelectron spectroscopy (XPS)
Issue Date: 5-Sep-2001
Source: Zhang, F.,Kang, E.T.,Neoh, K.G.,Wang, P.,Tan, K.L. (2001-09-05). Modification of Si(100) surface by the grafting of poly(ethylene glycol) for reduction in protein adsorption and platelet adhesion. Journal of Biomedical Materials Research 56 (3) : 324-332. ScholarBank@NUS Repository. https://doi.org/10.1002/1097-4636(20010905)56:3<324
Abstract: The modification of argon plasma-pretreated single-crystal Si(100) wafer surfaces via the UV-induced graft polymerization of poly(ethylene glycol) methacrylate (PEGMA) macromonomer (molecular weight ∼ 340) for biomaterials applications was explored. The modified Si(100) surfaces were characterized by X-ray photoelectron spectroscopy and atomic force microscopy. Surface peroxide concentrations resulting from the argon plasma treatment and subsequent atmospheric exposure were determined by a coupling reaction with diphenylpicrylhydrazyl. The results suggested that a short plasma treatment time of 10 s and brief air exposure were sufficient for generating an optimum amount of peroxides and hydroperoxides for the subsequent UV-induced graft polymerization. The graft concentration of the PEGMA polymer increased with increasing PEGMA macromonomer concentration for the graft polymerization and with increasing UV graft polymerization time. The PEGMA graft-polymerized silicon surface with a high poly(ethylene glycol) graft concentration was very effective in preventing protein adsorption and platelet adhesion. The grafted PEGMA polymer layer on the Si(100) surface exhibited fairly good stability during storage in a buffer solution. © 2001 John Wiley &amp; Sons, Inc.
Source Title: Journal of Biomedical Materials Research
URI: http://scholarbank.nus.edu.sg/handle/10635/66684
ISSN: 00219304
DOI: 10.1002/1097-4636(20010905)56:3<324
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

16
checked on Dec 7, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.