Please use this identifier to cite or link to this item:
|Title:||Modeling, simulation and operation performance of a simulated moving bed for enantioseparation of fluoxetine on new β-cyclodextrin columns|
Simulated moving bed
|Citation:||Yu, H.W., Ching, C.B. (2003-09). Modeling, simulation and operation performance of a simulated moving bed for enantioseparation of fluoxetine on new β-cyclodextrin columns. Adsorption 9 (3) : 213-223. ScholarBank@NUS Repository.|
|Abstract:||A Simulated Moving Bed (SMB) setup, including 8 new β-cyclodextrin columns, was used to achieve the enantioseparation of fluoxetine. The effects of feed concentration and feed flowrate on the operation performance parameters: purity, enrichment, recovery and productivity were studied. A simulation approach was applied to simulate the operation and performance of the simulated counter-current system. The model predicted the performance of the transient and cyclic steady state behaviour to a reasonably good extent. The adsorption isotherm and parameters determined by pulse experiments and moment analysis seem to be adequate in simulating both the transient and steady state behaviour. Generally, this model can provide guidance for designing operation condition of the SMB system.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 27, 2018
WEB OF SCIENCETM
checked on May 9, 2018
checked on Jun 8, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.