Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0021-9673(02)00840-3
Title: Enantiomer separation of flavour and fragrance compounds by liquid chromatography using novel urea-covalent bonded methylated β-cyclodextrins on silica
Authors: Ng, S.-C. 
Ong, T.-T. 
Fu, P. 
Ching, C.-B. 
Keywords: β-Cyclodextrin
Chiral stationary phases, LC
Enantiomer separation
Flavanones
Ionones
Issue Date: 30-Aug-2002
Source: Ng, S.-C.,Ong, T.-T.,Fu, P.,Ching, C.-B. (2002-08-30). Enantiomer separation of flavour and fragrance compounds by liquid chromatography using novel urea-covalent bonded methylated β-cyclodextrins on silica. Journal of Chromatography A 968 (1-2) : 31-40. ScholarBank@NUS Repository. https://doi.org/10.1016/S0021-9673(02)00840-3
Abstract: A novel methylated β-cyclodextrin chiral stationary phase (CSP-ME), which was chemically immobilised onto porous silica via multiple urea-linkages was synthesised. The CSP-ME chiral stationary phase depicted good enantiomer separation abilities for some well-known flavour as well as fragrance compounds using high-performance liquid chromatography under reverse phase conditions. The optimum resolution for α-ionone, 3-methyl-α-ionone, flavanone, 5-methoxyflavanone, 6-methoxyflavanone, 7-methoxyflavanone, hesperetin, naringenin and taxifolin was achieved using a mobile phase composition consisting of 1 wt.% triethylammonium acetate buffer (pH 4.68)-methanol. The effects of pH of triethylammonium acetate buffer and the methanol-acetonitrile content of the mobile phase composition on their retention time and resolution were examined to optimise the separation conditions. © 2002 Elsevier Science B.V. All rights reserved.
Source Title: Journal of Chromatography A
URI: http://scholarbank.nus.edu.sg/handle/10635/66580
ISSN: 00219673
DOI: 10.1016/S0021-9673(02)00840-3
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

59
checked on Dec 12, 2017

Page view(s)

44
checked on Dec 7, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.