Please use this identifier to cite or link to this item:
|Title:||Tunable spatial heterogeneity in structure and composition within aqueous microfluidic droplets|
|Authors:||Hui Sophia Lee, S.|
Kun Yap, S.
Alan Hatton, T.
|Citation:||Hui Sophia Lee, S., Wang, P., Kun Yap, S., Alan Hatton, T., Khan, S.A. (2012-04-26). Tunable spatial heterogeneity in structure and composition within aqueous microfluidic droplets. Biomicrofluidics 6 (2) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3694841|
|Abstract:||In this paper, we demonstrate biphasic microfluidic droplets with broadly tunable internal structures, from simple near-equilibrium drop-in-drop morphologies to complex yet uniform non-equilibrium steady-state structures. The droplets contain an aqueous mixture of poly(ethylene glycol) (PEG) and dextran and are dispensed into an immiscible oil in a microfluidic T-junction device. Above a certain well-defined threshold droplet speed, the inner dextran-rich phase is "stirred" within the outer PEG-rich phase. The stirred polymer mixture is observed to exhibit a near continuum of speed and composition-dependent phase morphologies. There is increasing interest in the use of such aqueous two-phase systems in microfluidic devices for biomolecular applications in a variety of contexts. Our work presents a method to go beyond equilibrium phase morphologies in generating microfluidic "multiple" emulsions and at the same time raises the possibility of biochemical experimentation in benign yet complex biomimetic milieus. © 2012 American Institute of Physics.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 24, 2018
WEB OF SCIENCETM
checked on May 16, 2018
checked on May 5, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.