Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.3694841
Title: Tunable spatial heterogeneity in structure and composition within aqueous microfluidic droplets
Authors: Hui Sophia Lee, S.
Wang, P.
Kun Yap, S.
Alan Hatton, T.
Khan, S.A. 
Issue Date: 26-Apr-2012
Source: Hui Sophia Lee, S., Wang, P., Kun Yap, S., Alan Hatton, T., Khan, S.A. (2012-04-26). Tunable spatial heterogeneity in structure and composition within aqueous microfluidic droplets. Biomicrofluidics 6 (2) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3694841
Abstract: In this paper, we demonstrate biphasic microfluidic droplets with broadly tunable internal structures, from simple near-equilibrium drop-in-drop morphologies to complex yet uniform non-equilibrium steady-state structures. The droplets contain an aqueous mixture of poly(ethylene glycol) (PEG) and dextran and are dispensed into an immiscible oil in a microfluidic T-junction device. Above a certain well-defined threshold droplet speed, the inner dextran-rich phase is "stirred" within the outer PEG-rich phase. The stirred polymer mixture is observed to exhibit a near continuum of speed and composition-dependent phase morphologies. There is increasing interest in the use of such aqueous two-phase systems in microfluidic devices for biomolecular applications in a variety of contexts. Our work presents a method to go beyond equilibrium phase morphologies in generating microfluidic "multiple" emulsions and at the same time raises the possibility of biochemical experimentation in benign yet complex biomimetic milieus. © 2012 American Institute of Physics.
Source Title: Biomicrofluidics
URI: http://scholarbank.nus.edu.sg/handle/10635/64755
ISSN: 19321058
DOI: 10.1063/1.3694841
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

7
checked on Dec 13, 2017

WEB OF SCIENCETM
Citations

6
checked on Dec 13, 2017

Page view(s)

34
checked on Dec 9, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.