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|Title:||Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye|
|Keywords:||Human embryonic stem cells|
|Citation:||Oh, S.K.W., Chua, P., Foon, K.L., Ng, E., Chin, A., Choo, A.B.H., Srinivasan, R. (2009-05). Quantitative identification of teratoma tissues formed by human embryonic stem cells with TeratomEye. Biotechnology Letters 31 (5) : 653-658. ScholarBank@NUS Repository. https://doi.org/10.1007/s10529-009-9928-1|
|Abstract:||An automated vision system, TeratomEye, was developed for the identification of three representative tissue types: muscle, gut and neural epithelia which are commonly found in teratomas formed from human embryonic stem cells. Muscle tissue, a common structure was identified with an accuracy of 90.3% with high specificity and sensitivity greater than 90%. Gut epithelia were identified with an accuracy of 87.5% with specificity and sensitivity greater than 80%. Neural epithelia which were the most difficult structures to distinguish gave an accuracy of 47.6%. TeratomEye is therefore useful for the automated identification of differentiated tissues in teratoma sections.|
|Source Title:||Biotechnology Letters|
|Appears in Collections:||Staff Publications|
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