Please use this identifier to cite or link to this item:
|Title:||Interaction and complexation of phospholipid vesicles and triblock copolymers|
|Source:||Chieng, Y.Y., Chen, S.B. (2009-12-11). Interaction and complexation of phospholipid vesicles and triblock copolymers. Journal of Physical Chemistry B 113 (45) : 14934-14942. ScholarBank@NUS Repository. https://doi.org/10.1021/jp906929u|
|Abstract:||Mixtures of Pluronic (F-127 or L-61) and phospholipid were investigated for a wide range of Pluronic concentrations (0-15 wt %) using dynamic light scattering, differential scanning calorimetry, and fluorescence microscopy. The present study is aimed at better understanding how the amphiphilic triblock copolymers affect the lipid vesicles, particularly in the high-concentration regime. Our results show that L-61 interacts more strongly with phospholipid vesicles than F-127 when the copolymer is at the unimer state in the solution. For high concentrations, F-127 forms mixed micelles with solubilized lipid molecules in the form of bilayer patches. This novel behavior was observed for the first time. In contrast, more hydrophobic L-61 tends to precipitate with the solubilized lipids as large crew-cut mixed aggregates. © 2009 American Chemical Society.|
|Source Title:||Journal of Physical Chemistry B|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 19, 2017
WEB OF SCIENCETM
checked on Nov 21, 2017
checked on Dec 17, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.