Please use this identifier to cite or link to this item:
|Title:||Formulation of Fe3O4/acrylate co-polymer nanocomposites as potential drug carriers|
|Citation:||Phanapavudhikul, P., Shen, S., Ng, W.K., Tan, R.B.H. (2008-03). Formulation of Fe3O4/acrylate co-polymer nanocomposites as potential drug carriers. Drug Delivery 15 (3) : 177-183. ScholarBank@NUS Repository. https://doi.org/10.1080/10717540801952597|
|Abstract:||Magnetic nanocomposite particles were synthesized by encapsulating nanosized magnetite with an acrylate-based cationic co-polymer made of MMA, BA, and QMA and modifying with MeOPEGMA using the water replacement method. The composition of the co-polymer formulation was optimized based on zeta-potential measurements and freeze-thaw stability. Electrostatic interaction between negatively charged model drug aspirin and positively charged co-polymer plays the most important role in drug loading and in vitro release studies. Drug release exhibited a biphasic profile with an initial burst release followed by a prolonged slow release, which could be potentially useful for target and controlled drug delivery. Copyright © Informa Healthcare USA, Inc.|
|Source Title:||Drug Delivery|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Aug 13, 2018
WEB OF SCIENCETM
checked on Jul 4, 2018
checked on Jun 22, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.