Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.actbio.2005.09.005
Title: Production of ultra-fine bioresorbable carbonated hydroxyapatite
Authors: Murugan, R. 
Ramakrishna, S. 
Keywords: Carbonated hydroxyapatite
Elemental analysis
FTIR
Solubility
X-ray diffraction
Issue Date: Mar-2006
Source: Murugan, R., Ramakrishna, S. (2006-03). Production of ultra-fine bioresorbable carbonated hydroxyapatite. Acta Biomaterialia 2 (2) : 201-206. ScholarBank@NUS Repository. https://doi.org/10.1016/j.actbio.2005.09.005
Abstract: Ionic-substituted hydroxyapatite (HAp) based materials may be a better choice than pure HAp owing to their similarity in chemical composition with biological apatite. The present study reports a process for the production of carbonated hydroxyapatite (CHAp) using microwaves. The CHAp was evaluated for its phase purity, chemical homogeneity, functionality, morphology, and solubility. The CHAp thus obtained was compared with a pure HAp and a biological apatite, which provides quite an interesting insight into the carbonate substitution. The in vitro ionic dissolution rates determined under physiological conditions clearly demonstrate the soluble nature of CHAp compared to HAp. The overall results indicate that the processed CHAp has increased resorption relative to pure HAp and has a chemical composition corresponding to some extent with that of biological apatite. © 2005 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
Source Title: Acta Biomaterialia
URI: http://scholarbank.nus.edu.sg/handle/10635/61162
ISSN: 17427061
DOI: 10.1016/j.actbio.2005.09.005
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