Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.icheatmasstransfer.2006.11.007
Title: Numerical study of mass transfer coefficient in a 3D flat-plate rectangular microchannel bioreactor
Authors: Zeng, Y. 
Lee, T.-S. 
Yu, P. 
Low, H.-T. 
Keywords: Cell culture
Mass transport
Microchannel bioreactor
Issue Date: Feb-2007
Source: Zeng, Y., Lee, T.-S., Yu, P., Low, H.-T. (2007-02). Numerical study of mass transfer coefficient in a 3D flat-plate rectangular microchannel bioreactor. International Communications in Heat and Mass Transfer 34 (2) : 217-224. ScholarBank@NUS Repository. https://doi.org/10.1016/j.icheatmasstransfer.2006.11.007
Abstract: Microchannel bioreactors have been used in many studies to investigate the fluid microenvironment around cells. In the present study, a three-dimensional numerical model was developed to simulate the fluid flow and mass transfer in a 3D flat-plate rectangular microchannel bioreactor with a monolayer of cells adherent to the bottom. The numerical results of mass transfer were well correlated in terms of two dimensionless parameters: Sherwood number at base (Sh) and effective distance (κ). The generalized results show the mass transfer characteristic in the flat-plate microchannel bioreactors, which may find applications in culturing cells in these bioreactors. © 2006 Elsevier B.V. All rights reserved.
Source Title: International Communications in Heat and Mass Transfer
URI: http://scholarbank.nus.edu.sg/handle/10635/60965
ISSN: 07351933
DOI: 10.1016/j.icheatmasstransfer.2006.11.007
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