Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ijheatmasstransfer.2008.06.021
Title: Fluid dynamics and oxygen transport in a micro-bioreactor with a tissue engineering scaffold
Authors: Yu, P. 
Lee, T.S. 
Zeng, Y. 
Low, H.T. 
Keywords: Interface coupling
Micro-bioreactor
Oxygen transport
Porous-fluid interface
Swirling flow
Tissue engineering scaffold
Issue Date: 15-Jan-2009
Source: Yu, P.,Lee, T.S.,Zeng, Y.,Low, H.T. (2009-01-15). Fluid dynamics and oxygen transport in a micro-bioreactor with a tissue engineering scaffold. International Journal of Heat and Mass Transfer 52 (1-2) : 316-327. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ijheatmasstransfer.2008.06.021
Abstract: The flow environment in the micro-bioreactor with a tissue engineering scaffold was numerically modeled. The finite volume method based on multi-block grid was applied to simulate the coupled flow and oxygen transport in both porous medium and homogenous fluid regions. At porous-fluid interface, a stress jump condition that includes both viscous and inertial effects was imposed. A parametric study was performed to investigate the effects of Reynolds, Darcy, and Damkohler numbers on the flow and oxygen concentration fields inside and outside the scaffold. The minimum oxygen concentration in the scaffold and its location under different conditions were summarized. © 2008 Elsevier Ltd. All rights reserved.
Source Title: International Journal of Heat and Mass Transfer
URI: http://scholarbank.nus.edu.sg/handle/10635/60347
ISSN: 00179310
DOI: 10.1016/j.ijheatmasstransfer.2008.06.021
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