Please use this identifier to cite or link to this item:
|Title:||Characterization of neural stem cells on electrospun poly(L-lactic acid) nanofibrous scaffold|
Neural stem cell
Neural tissue engineering
|Source:||Yang, F., Xu, C.Y., Kotaki, M., Wang, S., Ramakrishna, S. (2004). Characterization of neural stem cells on electrospun poly(L-lactic acid) nanofibrous scaffold. Journal of Biomaterials Science, Polymer Edition 15 (12) : 1483-1497. ScholarBank@NUS Repository. https://doi.org/10.1163/1568562042459733|
|Abstract:||Nanofibrous poly(L-lactic acid) (PLLA) scaffolds were fabricated by an electrospinning technique and characterized by scanning electron microscopy, mercury porosimeter, atomic force microscopy and contact-angle test, The produced PLLA fibers with diameters ranging from 150 to 350 nm were randomly orientated with interconnected pores varying from several μm to about 140 μm in-between to form a three-dimensional architecture, which resembles the natural extracellular matrix structure in human body. The in vitro cell culture study was performed and the results indicate that the nanofibrous scaffold not only supports neural stem cell (NSC) differentiation and neurites out-growth, but also promotes NSC adhesion. The favorable interaction between the NSCs and the nanotibrous scaffold may be due to the greatly improved surface roughness of the electrospun nanofibrous scaffold. As evidenced by this study, the electrospun nanofibrous scaffold is expected to play a significant role in neural tissue engineering. © VSP 2004.|
|Source Title:||Journal of Biomaterials Science, Polymer Edition|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Feb 21, 2018
WEB OF SCIENCETM
checked on Jan 16, 2018
checked on Feb 18, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.