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Title: Evolutionary computing for knowledge discovery in medical diagnosis
Authors: Tan, K.C. 
Yu, Q.
Heng, C.M.
Lee, T.H. 
Keywords: Data mining
Evolutionary computing
Knowledge discovery
Medical diagnosis
Issue Date: Feb-2003
Citation: Tan, K.C., Yu, Q., Heng, C.M., Lee, T.H. (2003-02). Evolutionary computing for knowledge discovery in medical diagnosis. Artificial Intelligence in Medicine 27 (2) : 129-154. ScholarBank@NUS Repository.
Abstract: One of the major challenges in medical domain is the extraction of comprehensible knowledge from medical diagnosis data. In this paper, a two-phase hybrid evolutionary classification technique is proposed to extract classification rules that can be used in clinical practice for better understanding and prevention of unwanted medical events. In the first phase, a hybrid evolutionary algorithm (EA) is utilized to confine the search space by evolving a pool of good candidate rules, e.g. genetic programming (GP) is applied to evolve nominal attributes for free structured rules and genetic algorithm (GA) is used to optimize the numeric attributes for concise classification rules without the need of discretization. These candidate rules are then used in the second phase to optimize the order and number of rules in the evolution for forming accurate and comprehensible rule sets. The proposed evolutionary classifier (EvoC) is validated upon hepatitis and breast cancer datasets obtained from the UCI machine-learning repository. Simulation results show that the evolutionary classifier produces comprehensible rules and good classification accuracy for the medical datasets. Results obtained from t-tests further justify its robustness and invariance to random partition of datasets. © 2003 Elsevier Science B.V. All rights reserved.
Source Title: Artificial Intelligence in Medicine
ISSN: 09333657
DOI: 10.1016/S0933-3657(03)00002-2
Appears in Collections:Staff Publications

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