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Please use this identifier to cite or link to this item: https://doi.org/10.1063/1.3505152
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dc.titleCapturing a DNA duplex under near-physiological conditions
dc.contributor.authorZhang, H.
dc.contributor.authorXu, W.
dc.contributor.authorLiu, X.
dc.contributor.authorStellacci, F.
dc.contributor.authorThong, J.T.L.
dc.date.accessioned2014-06-17T02:40:57Z
dc.date.available2014-06-17T02:40:57Z
dc.date.issued2010-10-18
dc.identifier.citationZhang, H., Xu, W., Liu, X., Stellacci, F., Thong, J.T.L. (2010-10-18). Capturing a DNA duplex under near-physiological conditions. Applied Physics Letters 97 (16) : -. ScholarBank@NUS Repository. https://doi.org/10.1063/1.3505152
dc.identifier.issn00036951
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/55253
dc.description.abstractWe report in situ trapping of a thiolated DNA duplex with eight base pairs into a polymer-protected gold nanogap device under near-physiological conditions. The double-stranded DNA was captured by electrophoresis and covalently attached to the nanogap electrodes through sulfur-gold bonding interaction. The immobilization of the DNA duplex was confirmed by direct electrical measurements under near-physiological conditions. The conductance of the DNA duplex was estimated to be 0.09 μS. We also demonstrate the control of DNA dehybridization by heating the device to temperatures above the melting point of the DNA. © 2010 American Institute of Physics.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1063/1.3505152
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentCHEMISTRY
dc.contributor.departmentELECTRICAL & COMPUTER ENGINEERING
dc.description.doi10.1063/1.3505152
dc.description.sourcetitleApplied Physics Letters
dc.description.volume97
dc.description.issue16
dc.description.page-
dc.description.codenAPPLA
dc.identifier.isiut000283502100082
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