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|Title:||A Markovian approach to the control of genetic regulatory networks|
|Authors:||Chen, P.C.Y. |
|Source:||Chen, P.C.Y., Chen, J.W. (2007-09). A Markovian approach to the control of genetic regulatory networks. BioSystems 90 (2) : 535-545. ScholarBank@NUS Repository. https://doi.org/10.1016/j.biosystems.2006.12.005|
|Abstract:||This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while state transitions are considered to be probabilistic. An algorithm is proposed to determine a sequence of control actions that drives (without state feedback) the state of a given network to within a desired state set with a prescribed minimum or maximum probability. A heuristic is proposed and shown to improve the efficiency of the algorithm for a class of genetic networks. © 2007 Elsevier Ireland Ltd. All rights reserved.|
|Appears in Collections:||Staff Publications|
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