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https://scholarbank.nus.edu.sg/handle/10635/53779
Title: | FUNCTIONALIZATION OF POLYCAPROLACTONE THROUGH NOVEL BLOCK COPOLYMER DESIGN FOR CELL ENGINEERING AND GENE DELIVERY | Authors: | LI ZIBIAO | Keywords: | PCL, Biodegradable, Block Copolymer, Biomedical Application, Cell Engineering, Gene Delivery | Issue Date: | 23-Jul-2013 | Citation: | LI ZIBIAO (2013-07-23). FUNCTIONALIZATION OF POLYCAPROLACTONE THROUGH NOVEL BLOCK COPOLYMER DESIGN FOR CELL ENGINEERING AND GENE DELIVERY. ScholarBank@NUS Repository. | Abstract: | In this thesis, biodegradable block copolymers with various architectures containing aliphatic polycaprolactone (PCL) and different functional components were designed to manipulate the amphiphilicity, mechanical properties, degradation rate and functionalities of the desired products. The potential applications of the newly developed block copolymers in cell engineering and gene delivery were explored and demonstrated. These studies have diversified a new group of PCL-based biodegradable block copolymers and the results obtained could be helpful in clarifying block copolymer design considerations for specific biomedical applications | URI: | http://scholarbank.nus.edu.sg/handle/10635/53779 |
Appears in Collections: | Ph.D Theses (Open) |
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