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|Title:||Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature|
Dynamic vessel analyzer
Retinal vascular imaging
|Citation:||Lim, M., Sasongko, M.B., Ikram, M.K., Lamoureux, E., Wang, J.J., Wong, T.Y., Cheung, C.Y. (2013-04). Systemic Associations of Dynamic Retinal Vessel Analysis: A Review of Current Literature. Microcirculation 20 (3) : 257-268. ScholarBank@NUS Repository. https://doi.org/10.1111/micc.12026|
|Abstract:||Endothelial dysfunction is a key pathogenic mechanism of CVD. The retinal microvascular network offers a unique, non-invasive window to study endothelial function. Recently, dynamic measurement of retinal vessel caliber using flicker light stimulation has been used to evaluate potential endothelial dysfunction and other mechanisms in CVD. A variety of studies now indicate that retinal vasodilation during flicker light simulation is reduced in diabetes, hypertension, hyperlipidemia and obesity, and may be influenced by age and race/ethnicity. These data suggest that flicker light-induced retinal vasodilation may be a unique and non-invasive measure of endothelial dysfunction. This review focuses recent studies on systemic associations of flicker light-induced retinal vasodilation, and discusses the potential for future research in this area. © 2012 John Wiley & Sons Ltd.|
|Appears in Collections:||Staff Publications|
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