Please use this identifier to cite or link to this item:
|Title:||The relationships between dietary fat intake and risk of colorectal cancer: Evidence from the combined analysis of 13 case-control studies|
|Source:||Howe, G.R., Aronson, K.J., Benito, E., Castelleto, R., Cornée, J., Duffy, S., Gallagher, R.P., Iscovich, J.M., Deng-ao, J., Kaaks, R., Kune, G.A., Kune, S., Lee, H.P., Lee, M., Miller, A.B., Peters, R.K., Potter, J.D., Riboli, E., Slattery, M.L., Trichopoulos, D., Tuyns, A., Tzonou, A., Watson, L.F., Whittemore, A.S., Wu-Williams, A.H., Shu, Z. (1997). The relationships between dietary fat intake and risk of colorectal cancer: Evidence from the combined analysis of 13 case-control studies. Cancer Causes and Control 8 (2) : 215-228. ScholarBank@NUS Repository. https://doi.org/10.1023/A:1018476414781|
|Abstract:||The objective of this study was to examine the effects of the intake of dietary fat upon colorectal cancer risk in a combined analysis of data from 13 case-control studies previously conducted in populations with differing colorectal cancer rates and dietary practices. Original data records for 5,287 cases of colorectal cancer and 10,470 controls were combined. Logistic regression analysis was used to estimate odds ratios (OR) for intakes of total energy, total fat and its components, and cholesterol. Positive associations with energy intake were observed for 11 of the 13 studies. However, there was little, if any, evidence of any energy-independent effect of either total fat with ORs of 1.00, 0.95, 1.01, 1.02, and 0.92 for quintiles of residuals of total fat intake (P trend = 0.67) or for saturated fat with ORs of 1.00, 1.08, 1.06, 1.21, and 1.06 (P trend = 0.39). The analysis suggests that, among these case-control studies, there is no energy-independent association between dietary fat intake and risk of colorectal cancer. It also suggests that simple substitution of fat by other sources of calories is unlikely to reduce meaningfully the risk of colorectal cancer.|
|Source Title:||Cancer Causes and Control|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 7, 2017
WEB OF SCIENCETM
checked on Nov 23, 2017
checked on Dec 11, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.