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Title: Dietary effects on breast-cancer risk in Singapore
Authors: Lee, H.P. 
Gourley, L.
Duffy, S.W.
Estève, J.
Lee, J.
Day, N.E.
Issue Date: 1991
Citation: Lee, H.P.,Gourley, L.,Duffy, S.W.,Estève, J.,Lee, J.,Day, N.E. (1991). Dietary effects on breast-cancer risk in Singapore. Lancet 337 (8751) : 1197-1200. ScholarBank@NUS Repository.
Abstract: It is suspected that diet influences the risk of getting breast cancer. A study of diet and breast cancer was done among 200 Singapore Chinese women with histologically confirmed disease and 420 matched controls. A quantitative food-frequency questionnaire was used to assess intakes of selected nutrients and foods 1 year before interview. Daily intakes were computed and risk analysed after adjustment for concomitant risk factors. In premenopausal women, high intakes of animal proteins and red meat were associated with . increased risk. Decreased risk was associated with high intakes of polyunsaturated fatty acids (PUFA), beta-carotene, soya proteins, total soya products, a high PUFA to saturated fatty acid ratio, and a high proportion of soya to total protein. In multiple analysis, the variables which were significant after adjustment for each other were red meat (p < 0.001) as a predisposing factor, and PUFA (p=0.02), beta-carotene (p=0.003), and soya protein (p=0.02) as protective factors, the analysis of dietary variables in postmenopausal women gave uniformly non-significant results. Our finding that soya products may protect against breast cancer in younger women is of interest since these foods are rich in phyto-oestrogens.
Source Title: Lancet
ISSN: 01406736
Appears in Collections:Staff Publications

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