Please use this identifier to cite or link to this item:
|Title:||A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women|
|Source:||Butler, L.M.,Wu, A.H.,Wang, R.,Koh, W.-P.,Yuan, J.-M.,Yu, M.C. (2010-04-01). A vegetable-fruit-soy dietary pattern protects against breast cancer among postmenopausal Singapore Chinese women. American Journal of Clinical Nutrition 91 (4) : 1013-1019. ScholarBank@NUS Repository. https://doi.org/10.3945/ajcn.2009.28572|
|Abstract:||Background: Prospective epidemiologic studies in Asian populations consistently show that soy is protective against breast cancer. Objective: The objective was to prospectively evaluate whether the protective effect of soy is due to soy isoflavones alone or to their combination with other beneficial dietary factors in an Asian population. Design: Using principal components analysis, we previously identified a "meat-dim sum" pattern characterized by meat, starch, and dim sum items and a "vegetable-fruit- soy" pattern characterized by cruciferous vegetables, fruit, and tofu items in a population-based cohort of Singapore Chinese initiated between 1993 and 1998. Component scores representing intakes of each pattern were used in multivariable Cox regression models to analyze the relation between diet at baseline and breast cancer incidence. Results: As of 31 December 2005, 629 incident breast cancer cases had been diagnosed among the 34,028 women. With greater intake of the vegetable-fruit-soy dietary pattern, we observed a dose-dependent trend (P < 0.01) for decreasing breast cancer risk among postmenopausal women [hazard ratio (HR): 0.70; 95% CI: 0.51, 0.95 for the fourth compared with first quartile]. A stronger association for the vegetable-fruit-soy pattern was observed among postmenopausal women with ≥5 y of follow-up (HR: 0.57; 95% CI: 0.36, 0.88; P for trend <0.01). No trend was observed for a greater intake of the meat-dim sum dietary pattern and increased breast cancer risk. Conclusion: Our findings support the hypothesis that a diet characterized by vegetables, fruit, and soy has an early-acting protective effect on breast carcinogenesis. © 2010 American Society for Nutrition.|
|Source Title:||American Journal of Clinical Nutrition|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Dec 5, 2017
WEB OF SCIENCETM
checked on Nov 2, 2017
checked on Dec 9, 2017
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.