Please use this identifier to cite or link to this item: https://doi.org/10.1002/(SICI)1522-2683(19990101)20:1<198
Title: Chiral resolution of atropine, homatropine and eight synthetic tropinyl and piperidinyl esters by capillary zone electrophoresis with cyclodextrin additives
Authors: Jin, L.J.
Wang, Y. 
Xu, R.
Go, M.L. 
Lee, H.K. 
Li, S.F.Y. 
Keywords: Atropine
Capillary electrophoresis
Chiral
Cyclodextrins
Homatropine
Piperidinyl esters
Tropinyl esters
Issue Date: 1999
Source: Jin, L.J.,Wang, Y.,Xu, R.,Go, M.L.,Lee, H.K.,Li, S.F.Y. (1999). Chiral resolution of atropine, homatropine and eight synthetic tropinyl and piperidinyl esters by capillary zone electrophoresis with cyclodextrin additives. Electrophoresis 20 (1) : 198-203. ScholarBank@NUS Repository. https://doi.org/10.1002/(SICI)1522-2683(19990101)20:1<198
Abstract: Chiral resolution of atropine, homatropine and eight synthetic tropinyl and piperidinyl esters were studied by capillary zone electrophoresis with cyclodextrin additives. Atropine and eight synthetic derivatives were successfully resolved by heptakis-(2,3,6-tri-O-methyl)-β-cyclodextrin (TM- β-CD) at concentrations ranging from 10 to 40 mM. Homatropine was baseline resolved by 10 mM β-cyclodextrin and hydroxypropyl-β-cyclodextrin (HP-β- CD), respectively. The developed method was employed for the determination of atropine enantiomers in human serum.
Source Title: Electrophoresis
URI: http://scholarbank.nus.edu.sg/handle/10635/53278
ISSN: 01730835
DOI: 10.1002/(SICI)1522-2683(19990101)20:1<198
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