Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0925-4773(03)00120-5
Title: Ziwi, the zebrafish homologue of the Drosophila piwi: Co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults
Authors: Tan, C.-H. 
Lee, T.-C.
Weeraratne, S.D.
Korzh, V. 
Lim, T.-M. 
Gong, Z. 
Keywords: Central nervous system
Embryo
Embryogenesis
Fry
Genital ridge
Notochord
Ovary
Pectoral fins
piwi
Testis
vasa
Zebrafish
ziwi cDNA
Issue Date: Dec-2002
Source: Tan, C.-H.,Lee, T.-C.,Weeraratne, S.D.,Korzh, V.,Lim, T.-M.,Gong, Z. (2002-12). Ziwi, the zebrafish homologue of the Drosophila piwi: Co-localization with vasa at the embryonic genital ridge and gonad-specific expression in the adults. Mechanisms of Development 119 (SUPPL. 1) : S221-S224. ScholarBank@NUS Repository. https://doi.org/10.1016/S0925-4773(03)00120-5
Abstract: PIWI regulates the proliferation and maintenance of germline stem cells in diverse organisms. The full-length 3.26 kb ziwi cDNA, the zebrafish homologue of piwi of Drosophila, encodes a putative protein of 858 amino acids. ZIWI is 65% homologous with the mouse and human PIWI, but only 38 and 33% with Caenorhabditis elegans and Drosophila PIWI, respectively. In adult zebrafish, ziwi is expressed exclusively in the gonads. In embryos and fry, its expression is detectable initially during segmentation and persisted for at least 4 weeks post hatching. During neurogenesis and organogenesis, its expression was detected in the CNS and fin buds. Starting from 24 hpf and later on, ziwi transcripts were found in the genital ridge. © 2003 Elsevier Science Ireland Ltd. All rights reserved.
Source Title: Mechanisms of Development
URI: http://scholarbank.nus.edu.sg/handle/10635/53264
ISSN: 09254773
DOI: 10.1016/S0925-4773(03)00120-5
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