Please use this identifier to cite or link to this item:
|Title:||Kinetics and template nucleation of self-assembled hydroxyapatite nanocrystallites by chondroitin sulfate|
|Authors:||Jiang, H. |
|Citation:||Jiang, H., Liu, X.-Y., Zhang, G., Li, Y. (2005-12-23). Kinetics and template nucleation of self-assembled hydroxyapatite nanocrystallites by chondroitin sulfate. Journal of Biological Chemistry 280 (51) : 42061-42066. ScholarBank@NUS Repository. https://doi.org/10.1074/jbc.M412280200|
|Abstract:||Biomineralization is an important process, which is often assisted by biomolecules. In this paper, the effect of chondroitin sulfate on the crystallization of hydroxyapatite was examined quantitatively based on a generic heterogeneous nucleation model. It is found that chondroitin sulfate can suppress the supersaturation-driven interfacial structure mismatch between the hydroxyapatite crystal and the substrate and promote the formation of ordered hydroxyapatite nanocrystallite assemblies. The nucleation mechanism of self-aligned hydroxyapatite nanocrystallites was examined from the viewpoints of kinetics and interfacial structure and properties, which contributes to an understanding of the fundamentals of biomineralization of self-assembled structures. The results obtained from this study will provide a basic principle to design and fabricate highly orderly organic-inorganic hybrid materials. © 2005 by The American Society for Biochemistry and Molecular Biology, Inc.|
|Source Title:||Journal of Biological Chemistry|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 14, 2018
WEB OF SCIENCETM
checked on Jul 4, 2018
checked on Jun 8, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.