Please use this identifier to cite or link to this item: https://doi.org/10.1166/jnn.2008.502
Title: Fabrication and biofunctionalization of selenium-polypyrrole core-shell nanoparticles for targeting and imaging of cancer cells
Authors: Li, J.-L. 
Liu, X.-Y. 
Keywords: Cancer cells
Nanoparticle
Polypyrrole
Selenium
Transferrin
Issue Date: May-2008
Source: Li, J.-L., Liu, X.-Y. (2008-05). Fabrication and biofunctionalization of selenium-polypyrrole core-shell nanoparticles for targeting and imaging of cancer cells. Journal of Nanoscience and Nanotechnology 8 (5) : 2488-2491. ScholarBank@NUS Repository. https://doi.org/10.1166/jnn.2008.502
Abstract: Selenium-polypyrrole core-shell nanoparticles are fabricated by an in-situ polymerization process and functionalized with transferrin for targeting and imaging of human cervical cancer cells. The shell thickness and chemical composition of the as-synthesized particles can be manipulated by controlling the precursor concentration. The presence of the polymer layer can greatly increase the thermal stability of the selenium nanoparticles. The presence of transferrin molecules on the surface of the core-shell nanoparticles can significantly enhance their cellular uptake. The tranferrin-conjugated core-shell nanoparticles can be potentially used for the targeting and imaging of cancer cells. Copyright © 2008 American Scientific Publishers All rights reserved.
Source Title: Journal of Nanoscience and Nanotechnology
URI: http://scholarbank.nus.edu.sg/handle/10635/52930
ISSN: 15334880
DOI: 10.1166/jnn.2008.502
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