Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/52671
DC Field | Value | |
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dc.title | Optimization of the reversed-phase high-performance, liquid chromatographic separation of the enantiomers of a cationic chiral drug (tolperisone) on a heptakis(6-azido-6-deoxy) perphenylcarbamated β-cyclodextrin column | |
dc.contributor.author | Velmurugan, T. | |
dc.contributor.author | Ching, C.B. | |
dc.contributor.author | Ng, S.C. | |
dc.contributor.author | Bai, Z.W. | |
dc.contributor.author | Ong, T.T. | |
dc.date.accessioned | 2014-05-16T07:24:40Z | |
dc.date.available | 2014-05-16T07:24:40Z | |
dc.date.issued | 2002 | |
dc.identifier.citation | Velmurugan, T.,Ching, C.B.,Ng, S.C.,Bai, Z.W.,Ong, T.T. (2002). Optimization of the reversed-phase high-performance, liquid chromatographic separation of the enantiomers of a cationic chiral drug (tolperisone) on a heptakis(6-azido-6-deoxy) perphenylcarbamated β-cyclodextrin column. Chromatographia 56 (3-4) : 229-232. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00095893 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/52671 | |
dc.description.abstract | Heptakis(6-azido-6-deoxy) perphenylcarbamated β-cyclodextrin has been synthesized and chemically immobilized on silica gel for use as a chiral stationary phase (PC-CSP) for analytical separation of the enantiomers of chiral drugs. Separation of the enantiomers of tolperisone was studied by high-performance liquid chromatography under reversed-phase conditions. The chromatographic conditions were optimized by varying mobile phase pH, composition, ionic strength, and velocity; 40:60 methanol-1% triethylammonium acetate (TEAA) buffer, pH 5.5, was found to be the most suitable for this separation. | |
dc.source | Scopus | |
dc.subject | β-Cyclodextrin | |
dc.subject | Column liquid chromatography | |
dc.subject | Enantiomer separation | |
dc.subject | Optimizatio | |
dc.subject | Tolperisone | |
dc.type | Article | |
dc.contributor.department | CHEMICAL AND PROCESS ENGINEERING CENTRE | |
dc.contributor.department | CHEMISTRY | |
dc.contributor.department | CHEMICAL & ENVIRONMENTAL ENGINEERING | |
dc.description.sourcetitle | Chromatographia | |
dc.description.volume | 56 | |
dc.description.issue | 3-4 | |
dc.description.page | 229-232 | |
dc.description.coden | CHRGB | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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