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|Title:||A novel nano-microfibre PLGA scaffold for tendon/ ligament tissue engineering|
|Authors:||Sahoo, S. |
|Source:||Sahoo, S.,Ouyang, H.W.,Toh, S.L.,Goh, J.C.,Tay, T.E. (2004). A novel nano-microfibre PLGA scaffold for tendon/ ligament tissue engineering. Transactions - 7th World Biomaterials Congress : 8-. ScholarBank@NUS Repository.|
|Abstract:||The development of a biodegradable nano-microfiber polymer scaffold for tendon/ligament tissue engineering by electrospinning poly(D,L-lactide-co- glycolide) (PLGA) nanofibers, was described. About six knitted scaffolds of 20 mm width and 30 mm length were fabricated by knitting PLGA fibers comprising filaments of 25 μm diameter. The scaffolds were characterized by phase contrast microscopy and scanning electron microscopy (SEM). The phase contrast microscopy and SEM revealed that nanofibers ranging in diameters from 300 to 900 nm were randomly spread over the surface of the knitted scaffold. The results show that the developed scaffold holds promise in tissue engineering of tendon/ligament while the microfibers provide mechanical strength.|
|Source Title:||Transactions - 7th World Biomaterials Congress|
|Appears in Collections:||Staff Publications|
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