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|Title:||A discrete-event approach to transcription control with dynamic event-controllability|
Genetic regulatory networks
|Citation:||Chen, P.C.Y. (2006-11). A discrete-event approach to transcription control with dynamic event-controllability. Journal of Computational Biology 13 (9) : 1532-1545. ScholarBank@NUS Repository. https://doi.org/10.1089/cmb.2006.13.1532|
|Abstract:||This paper presents a discrete-event approach to the synthesis of transcription control for a class of (computational) gene networks. Given a set of genes and protein-gene and/or protein-protein interaction patterns, this approach can be used to synthesize a transcription control induced by these interaction patterns, and as a consequence, determine the behavior of the gene network. This proposed approach is demonstrated in the synthesis of a transcription control that produces the observed (logical) behavior in the induction of a phage λ lysogen. © Mary Ann Liebert, Inc.|
|Source Title:||Journal of Computational Biology|
|Appears in Collections:||Staff Publications|
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