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Title: Measuring health-state utilities for cost-utility analysis
Authors: WANG PEI
Keywords: health-state utilities, cost-utility analysis, utility assessment, preference-based instrument, time trade-off
Issue Date: 22-Aug-2013
Source: WANG PEI (2013-08-22). Measuring health-state utilities for cost-utility analysis. ScholarBank@NUS Repository.
Abstract: The health-state utility (HSU) is one of the key parameters in cost-utility analysis for informing decision making in healthcare resource allocation. In this thesis, I compared the HSU values between Singaporeans and mainland Chinese as well as between type 2 diabetes mellitus (T2DM) patients and the general population in Singapore. It was found that members of the general Singaporean population have lower HSU values than mainland Chinese and Singaporean T2DM patients. Given the differences detected, a HSU value set for EQ-5D-3L health states was estimated based on empirically measured health-state preferences of the general Singaporean population. The preference-based SF-6D instrument was also studied. A mapping function for predicting the SF-6D index score from the SF-8 health survey was developed and the discriminative power of the SF-6D index scores derived from the SF-36 was found to be more discriminative than the same index score derived from the SF-12.
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