Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/49361
Title: SPATIOTEMPORAL CONTROL OF THE SALT STRESS INDUCED TRANSCRIPTIONAL RESPONSE IN ARABIDOPSIS
Authors: WU RUI
Keywords: Arabidopsis root, salt stress, transcriptional regulation, spatiotemporal, CRE, synthetic promoter,
Issue Date: 22-Aug-2013
Source: WU RUI (2013-08-22). SPATIOTEMPORAL CONTROL OF THE SALT STRESS INDUCED TRANSCRIPTIONAL RESPONSE IN ARABIDOPSIS. ScholarBank@NUS Repository.
Abstract: My study is focused on how different signaling pathways are integrated spatiotemporally under salt stress and how transcriptional regulation occurs. Firstly, I did an analysis on a previously generated spatiotemporal transcriptional map of salt stress in Arabidopsis roots, covering 4 core cell types and 6 time points for salt treatment. Based on this spatiotemporal map, the transcriptional changes of key components in hormone biosynthesis and signaling were identified, and a bioinformatics method was also developed to systematically de-convolve the hormone crosstalk network with salt stress, identifying some salt stress response sub-modules controlled by hormone signaling. Second, I developed an efficient pipeline to study the biological functions of cis-regulatory elements which are good starting points for the generation of a CRE centered transcriptional network involved in the salt stress response in the Arabidopsis roots. Using this pipeline, I validated the regulatory functions of seven CREs and two other previously unknown elements.
URI: http://scholarbank.nus.edu.sg/handle/10635/49361
Appears in Collections:Ph.D Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
WuR.pdf.pdf2.79 MBAdobe PDF

OPEN

NoneView/Download

Page view(s)

134
checked on Jan 15, 2018

Download(s)

198
checked on Jan 15, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.