Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/48637
Title: ISOLATION, CHARACTERIZATION AND DETECTION OF BIOACTIVE COMPONENTS FROM BOTANICAL MATERIALS
Authors: WANG HONGYU
Keywords: proanthocyanidins, amylase, glucosidase, inhibition, starch, organosulfur
Issue Date: 17-May-2013
Source: WANG HONGYU (2013-05-17). ISOLATION, CHARACTERIZATION AND DETECTION OF BIOACTIVE COMPONENTS FROM BOTANICAL MATERIALS. ScholarBank@NUS Repository.
Abstract: Tannins have been found to be widely distributed in natural plants. However, characterization of tannins is difficult due to the linkage complexity and structural diversity of monomeric units. Therefore, this work investigated the characterization of tannins from natural plants using various analytical instruments and analytical methods. The isolated tannins exhibited potent alpha-amylase and alpha-glucosidase inhibitory activity. Tannin derivatives are also promising starch hydrolase inhibitors. Dracoflavan B, a procyanidin A2 derivative was identified and isolated from traditional medicine-dragon¿s blood. Its inhibitory activity and inhibition mechanism were investigated in this project. In addition, the interaction activity between proanthocyanidins and rice starch was discovered and characterized for the first time in this project. The second part investigated the hypochlorite scavenging activity of six organosulfur compounds mainly from garlic and cruciferous vegetables. Their oxidation mechanism was investigated through characterization of their oxidation products by hypochlorite.
URI: http://scholarbank.nus.edu.sg/handle/10635/48637
Appears in Collections:Ph.D Theses (Open)

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