Please use this identifier to cite or link to this item:
|Title:||Further evidence for an association between schizophrenia and the HLA DQB1 gene locus|
|Source:||Nimgaonkar, V.L., Zhang, X.R., Rudert, W.A., Trucco, M., Tsoi, W.-F., Saha, N. (1996). Further evidence for an association between schizophrenia and the HLA DQB1 gene locus. Schizophrenia Research 18 (1) : 43-49. ScholarBank@NUS Repository. https://doi.org/10.1016/0920-9964(95)00023-2|
|Abstract:||A case-control study was conducted in Singapore, in order to examine a proposed association between schizophrenia and the HLA DQB1 gene locus. The probands were male inpatients of Chinese ethnicity with schizophrenia (ICD-10 criteria, n = 102) and the controls were adults matched for gender and ethnicity (n = 111). Polymorphisms of the HLA DQB1 gene were examined using molecular typing by reverse dot-blotting (MTRB), a novel PCR based method. Among the patients, a positive association with HLA DQB1*0303 (odds ratio 4.46, C.I. 1.63, 12.17), as well as a negative association with HLA DQB1*0602 (odds ratio 0.22, C.I. 0.18, 0.83) was detected.|
|Source Title:||Schizophrenia Research|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 16, 2018
WEB OF SCIENCETM
checked on Nov 23, 2017
checked on Jan 13, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.