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|Title:||A comparison of safety, tolerability and immunogenicity of Oka/Merck varicella vaccine and VARILRIX™ in healthy children|
Varicella zoster virus
|Source:||Lau, Y.-L., Lee, T.-L., Vessey, S.J.R., Chan, I.S.F., Chan, C.Y., Kaplan, K.M., Distefano, D.J., Harmon, A.L., Golie, A., Hartzel, J., Xu, J., Li, S., Matthews, H., Sadoff, J.C., Shaw, A., Huang, L.-M., Lee, C.-Y., Lin, T.-Y., Lee, B.W., Kwan, K., Kasim, S.M. (2002). A comparison of safety, tolerability and immunogenicity of Oka/Merck varicella vaccine and VARILRIX™ in healthy children. Vaccine 20 (23-24) : 2942-2949. ScholarBank@NUS Repository. https://doi.org/10.1016/S0264-410X(02)00245-1|
|Abstract:||This study compared safety, tolerability, and immunogenicity of the Oka/Merck varicella vaccine and VARILRIX™ [Oka-RIT strain SmithKline Beecham Biologicals] in healthy children 12-24 months of age. Subjects were randomized in this double blind study to receive either a single dose of Oka/Merck varicella vaccine, (∼50,000 plaque forming units (PFU), Group A or ∼16,000PFU, Group B) or 1 dose of VARILRIX™, (∼40,000PFU/dose, Group C). Safety profiles in each treatment group were similar. The proportions of subjects achieving a 6-week postvaccination titer ≥5 gpELISA units in Groups A, B or C were 97.1, 95.2 and 85.6%, respectively. © 2002 Elsevier Science Ltd. All rights reserved.|
|Appears in Collections:||Staff Publications|
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