Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/47524
Title: DEVELOPMENT OF PLASMONIC NANOSTRUCTURES FOR BIOLOGICAL SENSING
Authors: NGUYEN THI VAN THANH
Keywords: Plasmonics, nanostructures, lithography, biosensing, DNA, Insulin
Issue Date: 17-Jan-2013
Source: NGUYEN THI VAN THANH (2013-01-17). DEVELOPMENT OF PLASMONIC NANOSTRUCTURES FOR BIOLOGICAL SENSING. ScholarBank@NUS Repository.
Abstract: In this thesis, it is aimed to develop plasmonic nanostructures for biological sensing applications by laser interference lithography technique which can greatly improve the fabrication flexibility, tune LSPR over a wide range of wavelength and facilitate the design of novel biosensors which are based on LSPR. The optical properties of various 2D fabricated plasmonic nanostructures are studied systematically with the supporting of finite difference time domain simulation method. In addition, these fabricated plasmonic nanostructures are used to demonstrate biological molecules sensing. With efficient principled detection designs to take advantages of high plasmonic enhancement of plasmonic nanostructures and high specificity of biological molecule interactions, the fabricated plasmonic nanostructures show to be efficient optical transducers in DNA, Insulin and Adenosine sensing with ultra-low detection limits and high selectivity. These works firmly imply that the fabricated plasmonic nanostructures can be utilized as an alternative sensor-on-chip approach to biological sensing.
URI: http://scholarbank.nus.edu.sg/handle/10635/47524
Appears in Collections:Ph.D Theses (Open)

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