Please use this identifier to cite or link to this item: https://doi.org/10.1097/ID.0b013e3182611ff6
Title: Statins, glucocorticoids, and nonsteroidal anti-inflammatory drugs: Their influence on implant healing
Authors: Fu, J.-H. 
Bashutski, J.D.
Al-Hezaimi, K.
Wang, H.-L.
Keywords: Bone healing
Dental implant
Drugs
Glucocorticoids
Medications
NSAIDs
Osseointegration
Statins
Issue Date: 2012
Citation: Fu, J.-H., Bashutski, J.D., Al-Hezaimi, K., Wang, H.-L. (2012). Statins, glucocorticoids, and nonsteroidal anti-inflammatory drugs: Their influence on implant healing. Implant Dentistry 21 (5) : 362-367. ScholarBank@NUS Repository. https://doi.org/10.1097/ID.0b013e3182611ff6
Abstract: This article aimed at exploring the effects of common systemic medications used in the United States and their effects on periimplant bone healing. An electronic search for articles evaluating the influence of systemic medications on periimplant bone healing was conducted using the PubMed (MEDLINE) database. Statins, when administered locally or systemically, were found to increase bone formation and density. A reduction in bone turnover and bone-to-implant contact was observed in animal models examining the effect of glucocorticoids on periimplant bone healing. Continued use of nonsteroidal anti-inflammatory drugs (NSAIDs) during or after implant placement was associated with reduced bone-to-implant contact, bone area, and bone density. Evidence seems to suggest that statins improve implant osseointegration. However, glucocorticoids and NSAIDs showed conflicting results. Therefore, more randomized clinical trials are needed to validate the effect of glucocorticoids and NSAIDs on periimplant bone healing. Copyright © 2012 by Lippincott Williams & Wilkins.
Source Title: Implant Dentistry
URI: http://scholarbank.nus.edu.sg/handle/10635/47137
ISSN: 10566163
DOI: 10.1097/ID.0b013e3182611ff6
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