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|Title:||Effects of incorporation of HA/ZrO2 into glass ionomer cement (GIC)|
|Citation:||Gu, Y.W., Yap, A.U.J., Cheang, P., Khor, K.A. (2005). Effects of incorporation of HA/ZrO2 into glass ionomer cement (GIC). Biomaterials 26 (7) : 713-720. ScholarBank@NUS Repository. https://doi.org/10.1016/j.biomaterials.2004.03.019|
|Abstract:||Glass ionomer cements (GICs) are a class of bioactive cements that bond directly to bone. In this paper, a new bioactive hydroxyapatite (HA)/zirconia (ZrO2)-filled GIC composite was developed to improve the biocompatibility and bioactivity of the GICs with the surrounding bone and connective tissues. Nano-sized HA/30wt% ZrO2 powders were heat treated at 700°C and 800°C for 3h to elucidate the influence of the crystallinity of composite powders on the performance of HA/ZrO 2-GICs. The effects of different volume percentages of HA/ZrO 2 powders (4, 12, 28 and 40vol%) substituted within GICs were investigated based on their microhardness, compressive strength and diametral tensile strength. The HA/ZrO2-GICs composite was soaked in distilled water for 1 day and 1 week before subjecting the samples to mechanical testing. Results showed that the glass and HA/ZrO2 particles were distributed uniformly in the GIC matrix. The substitution of highly crystalline HA/ZrO 2 improved the mechanical properties of the HA/ZrO2-GICs due to the slow resorption rate for highly crystalline powders in distilled water. The mechanical properties of HA/ZrO2-GICs increased with increasing soak time due to the continuous formation of aluminium salt bridges, which improved the final strength of the cements. The compositions 4 and 12vol% HA/ZrO2-GICs exhibited superior mechanical properties than the original GICs. The mechanical properties of HA/ZrO2-GICs were found to be much better than those of HA-GICs because ZrO2 has the attributes of high strength, high modulus, and is significantly harder than glass and HA particles. Furthermore, ZrO2 does not dissolve with increasing soaking time. © 2004 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Staff Publications|
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