Please use this identifier to cite or link to this item: https://doi.org/10.1093/nar/gni147
Title: A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays
Authors: Ning, K.
Choi, K.P. 
Leong, H.W. 
Zhang, L. 
Issue Date: 2005
Source: Ning, K., Choi, K.P., Leong, H.W., Zhang, L. (2005). A post-processing method for optimizing synthesis strategy for oligonucleotide microarrays. Nucleic Acids Research 33 (17) : 1-6. ScholarBank@NUS Repository. https://doi.org/10.1093/nar/gni147
Abstract: The broad applicability of gene expression profiling to genomic analyses has generated huge demand for mass production of microarrays and hence for improving the cost effectiveness of microarray fabrication. We developed a post-processing method for deriving a good synthesis strategy. In this paper, we assessed all the known efficient methods and our post-processing method for reducing the number of synthesis cycles for manufacturing a DNA-chip of a given set of oligos. Our experimental results on both simulated and 52 real datasets show that no single method consistently gives the best synthesis strategy, and post-processing an existing strategy is necessary as it often reduces the number of synthesis cycles further. © The Author 2005. Published by Oxford University Press. All rights reserved.
Source Title: Nucleic Acids Research
URI: http://scholarbank.nus.edu.sg/handle/10635/43120
ISSN: 03051048
DOI: 10.1093/nar/gni147
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

6
checked on Dec 6, 2017

WEB OF SCIENCETM
Citations

9
checked on Nov 18, 2017

Page view(s)

57
checked on Dec 10, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.