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|Title:||Polynomial-time algorithms for building a consensus MUL-tree|
|Authors:||Cui, Y. |
multi-labeled phylogenetic tree multiset
|Source:||Cui, Y., Jansson, J., Sung, W.-K. (2012). Polynomial-time algorithms for building a consensus MUL-tree. Journal of Computational Biology 19 (9) : 1073-1088. ScholarBank@NUS Repository. https://doi.org/10.1089/cmb.2012.0008|
|Abstract:||A multi-labeled phylogenetic tree, or MUL-tree, is a generalization of a phylogenetic tree that allows each leaf label to be used many times. MUL-trees have applications in biogeography, the study of host-parasite cospeciation, gene evolution studies, and computer science. Here, we consider the problem of inferring a consensus MUL-tree that summarizes a given set of conflicting MUL-trees, and present the first polynomial-time algorithms for solving it. In particular, we give a straightforward, fast algorithm for building a strict consensus MUL-tree for any input set of MUL-trees with identical leaf label multisets, as well as a polynomial-time algorithm for building a majority rule consensus MUL-tree for the special case where every leaf label occurs at most twice. We also show that, although it is NP-hard to find a majority rule consensus MUL-tree in general, the variant that we call the singular majority rule consensus MUL-tree can be constructed efficiently whenever it exists. © 2012, Mary Ann Liebert, Inc.|
|Source Title:||Journal of Computational Biology|
|Appears in Collections:||Staff Publications|
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