Please use this identifier to cite or link to this item: https://doi.org/10.1186/1471-2164-12-S2-S6
Title: CAMBer: An approach to support comparative analysis of multiple bacterial strains
Authors: Wozniak, M. 
Wong, L. 
Tiuryn, J.
Issue Date: 2011
Source: Wozniak, M., Wong, L., Tiuryn, J. (2011). CAMBer: An approach to support comparative analysis of multiple bacterial strains. BMC Genomics 12 (SUPPL.2). ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2164-12-S2-S6
Abstract: Background: There is a large amount of inconsistency in gene structure annotations of bacterial strains. This inconsistency is a frustrating impedance to effective comparative genomic analysis of bacterial strains in promising applications such as gaining insights into bacterial drug resistance.Results: Here, we propose CAMBer as an approach to support comparative analysis of multiple bacterial strains. CAMBer produces what we called multigene families. Each multigene family reveals genes that are in one-to-one correspondence in the bacterial strains, thereby permitting their annotations to be integrated. We present results of our method applied to three human pathogens: Escherichia coli, Mycobacterium tuberculosis and Staphylococcus aureus.Conclusions: As a result, more accurate and more comprehensive annotations of the bacterial strains can be produced. © 2011 Wozniak et al; licensee BioMed Central Ltd.
Source Title: BMC Genomics
URI: http://scholarbank.nus.edu.sg/handle/10635/39291
ISSN: 14712164
DOI: 10.1186/1471-2164-12-S2-S6
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