Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/38806
Title: BACTERIAL BIOFILM FORMATION UNDER ANTIBACTERIAL STRESS AND IN SYMBIOTIC CULTURE
Authors: AMIT KUMAR
Keywords: AFM force spectroscopy, Biofilm, DLVO, Proteins and Metabolites, Pseudomonas aeruginosa, Staphylococcus aureus
Issue Date: 11-Jan-2013
Source: AMIT KUMAR (2013-01-11). BACTERIAL BIOFILM FORMATION UNDER ANTIBACTERIAL STRESS AND IN SYMBIOTIC CULTURE. ScholarBank@NUS Repository.
Abstract: Traditionally, bacterial systems are viewed as a collection of identical, individual cells growing in pure planktonic cultures in laboratory flasks, incognizant of and unaffected by the presence of other cells in the vicinity. However, it has gradually become clearer that bacterial cultures are highly heterogeneous and more often exist in other life forms, in symbiosis with a multitude of organisms. This study investigates some aspects of biofilm formation, interspecies interactions and culture heterogeneity in bacterial systems. In particular, bacterial mortality and biofilm formation in the presence of antibacterial stress were examined and modeled. In addition, the molecular changes taking place on bacterial surface under antibacterial stress and in symbiotic culture were identified. Results indicate that bacterial cultures respond to antibacterial stress to counter its effect and facilitate biofilm formation. In symbiotic culture, bacteria respond in a remarkably similar fashion as they do under antibacterial stress.
URI: http://scholarbank.nus.edu.sg/handle/10635/38806
Appears in Collections:Ph.D Theses (Open)

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
01Summary.pdf8.91 MBAdobe PDF

OPEN

NoneView/Download
02Chapter1.pdf237.23 kBAdobe PDF

OPEN

NoneView/Download
03Chapter2.pdf3.14 MBAdobe PDF

OPEN

NoneView/Download
04Chapter3.pdf1.26 MBAdobe PDF

OPEN

NoneView/Download
05Chapter4.pdf4.09 MBAdobe PDF

OPEN

NoneView/Download
06Chapter5.pdf6.04 MBAdobe PDF

OPEN

NoneView/Download
07Chapter6.pdf7.54 MBAdobe PDF

OPEN

NoneView/Download
08Chapter7.pdf1.16 MBAdobe PDF

OPEN

NoneView/Download
09Chapter8.pdf3.41 MBAdobe PDF

OPEN

NoneView/Download
10Chapter9.pdf284.59 kBAdobe PDF

OPEN

NoneView/Download
11References.pdf513.08 kBAdobe PDF

OPEN

NoneView/Download
12Appendices.pdf870.12 kBAdobe PDF

OPEN

NoneView/Download

Page view(s)

236
checked on Dec 11, 2017

Download(s)

436
checked on Dec 11, 2017

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.