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|Title:||Toxins in anti-nociception and anti-inflammation|
|Source:||Rajendra, W., Armugam, A., Jeyaseelan, K. (2004). Toxins in anti-nociception and anti-inflammation. Toxicon 44 (1) : 1-17. ScholarBank@NUS Repository. https://doi.org/10.1016/j.toxicon.2004.04.014|
|Abstract:||The use of toxins as novel molecular probes to study the structure-function relationship of ion-channels and receptors as well as potential therapeutics in the treatment of wide variety of diseases is well documented. The high specificity and selectivity of these toxins have attracted a great deal of interest as candidates for drug development. This review highlights the involvement of the proteins and peptide toxins as well as non-proteinaceous compounds derived from both venomous and non-venomous animals, in anti-nociception and anti-inflammation. The possible mechanisms of these potential therapeutic agents and possible clinical applications in the treatment of pain and inflammation are also summarized. © 2004 Elsevier Ltd. All rights reserved.|
|Appears in Collections:||Staff Publications|
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