Please use this identifier to cite or link to this item: https://doi.org/10.1016/0014-5793(90)81155-H
Title: Calcium ion activation of the anion-conducting channel in the rat liver mitochondrial inner membrane
Authors: Selwyn, M.J. 
Ng, C.L.T.
Choo, H.L.
Keywords: Anion channel
Calcium ion
Mitochondrial inner membrane
Mitochondrion
Issue Date: 1990
Source: Selwyn, M.J.,Ng, C.L.T.,Choo, H.L. (1990). Calcium ion activation of the anion-conducting channel in the rat liver mitochondrial inner membrane. FEBS Letters 269 (1) : 205-208. ScholarBank@NUS Repository. https://doi.org/10.1016/0014-5793(90)81155-H
Abstract: Stimulation of the rat liver mitochondrial inner-membrane anion-conducting channel by aeration is dependent on the concentration of Ca2+ ions in the assay medium. Ca2+ activates anion conduction in both aerated and non-energised mitochondria but acts over a wider concentration range and produces a greater increase in anion-conductivity in aerated mitochondria. EGTA reverse Ca2+ stimulation but takes several seconds to act, indicating slow release of Ca2+ from the activation site possibly on the matrix side of the inner mitochondrial membrane. It is suggested that this channel may respond to hormone-induced changes in cytosolic Ca2+ concentration.
Source Title: FEBS Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/38181
ISSN: 00145793
DOI: 10.1016/0014-5793(90)81155-H
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