Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/37883
Title: EPIDEMIOLOGY AND SPECIFIC RISK FACTORS FOR MALIGNANT LYMPHOMA IN THE SINGAPORE POPULATION
Authors: WONG KIN YOKE
Keywords: Asian, APC modelling, epidemiology, lymphoid neoplasms, risk factors, trends
Issue Date: 24-Sep-2012
Source: WONG KIN YOKE (2012-09-24). EPIDEMIOLOGY AND SPECIFIC RISK FACTORS FOR MALIGNANT LYMPHOMA IN THE SINGAPORE POPULATION. ScholarBank@NUS Repository.
Abstract: The incidence of lymphoid neoplasms has been rising steadily over the past decades in Singapore, and there were no apparent reasons to account for Singapore having the highest rate in Asia. We explored the influence of temporal variation on lymphoma rates by age-period-cohort modelling on individuals aged 15 to 79 years, using incidence data from the national cancer registry for the period 1968 to 2007. The results showed cohort effect has a significant impact on the trends of lymphoma, on top of age effect. We further investigated the aetiology factors in the Singapore Lymphoma Study, a hospital-based case-control study from 2004-2008. It was found that lifestyle behaviours, i.e. regular sunlight exposure during outdoor leisure activities, and alcohol consumption regardless of beverage types might be inversely associated with non-Hodgkin lymphoma risk. Working in a teaching profession increased NHL risk, but no association between cigarette smoking and risk of lymphoma was detected.
URI: http://scholarbank.nus.edu.sg/handle/10635/37883
Appears in Collections:Ph.D Theses (Open)

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