Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/37663
Title: CHARACTERIZATION OF A PLANT-SPECIFIC PRC1 (POLYCOMB REPRESSIVE COMPLEX 1)- LIKE COMPLEX AND ITS ROLE IN FLOWERING-TIME REGULATION
Authors: WANG YIZHONG
Keywords: PRC1, EMF1, Flowering time, Arabidopsis
Issue Date: 8-Aug-2012
Source: WANG YIZHONG (2012-08-08). CHARACTERIZATION OF A PLANT-SPECIFIC PRC1 (POLYCOMB REPRESSIVE COMPLEX 1)- LIKE COMPLEX AND ITS ROLE IN FLOWERING-TIME REGULATION. ScholarBank@NUS Repository.
Abstract: POLYCOMB GROUP (PCG) PROTEINS ARE WELL KNOWN FOR THEIR FUNCTION OF REPRESSING GENE EXPRESSION VIA REPRESSIVE CHROMATIN MODIFICATIONS. IN DROSOPHILA AND MAMMALS, PCG-MEDIATED SILENCING REQUIRES POLYCOMB REPRESSIVE COMPLEX 1 (PRC1). IN PLANTS PRC1-LIKE COMPLEXES REMAIN ELUSIVE. RECENT STUDIES SUGGEST THAT THE ARABIDOPSIS PROTEIN LHP1 (FOR LIKE HETEROCHROMATIN PROTEIN 1) PLAYS A PRC1-LIKE ROLE TO REPRESS GENE EXPRESSION. IN THIS STUDY, USING GENETIC AND MOLECULAR TOOLS I FOUND THAT A PLANT-SPECIFIC PROTEIN, EMBRYONIC FLOWER 1 (EMF1), FUNCTIONS AS PART OF A PRC1-LIKE COMPLEX CONTAINING LHP1 TO SILENCE GENE EXPRESSION. IN ADDITION, THIS EMF1-PRC1 COMPLEX ALSO INVOLVES OTHER PROTEINS. FURTHERMORE, I FOUND THAT EMF1 CONTROLS THE EXPRESSION OF FLOWERING LOCUS T (FT; ENCODING FLORIGEN) TO REGULATE FLOWERING TIME IN ARABIDOPSIS.
URI: http://scholarbank.nus.edu.sg/handle/10635/37663
Appears in Collections:Ph.D Theses (Open)

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