Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/37624
Title: ENCAPSULATION OF PLATINUM-BASED DERIVATIVES WITHIN CARBON NANOTUBES: INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION
Authors: LI JIAN
Keywords: carbon nanotube, platinum-based derivatives, drug delivery, controlled release, encapsulation, biodistribution
Issue Date: 11-Jan-2013
Source: LI JIAN (2013-01-11). ENCAPSULATION OF PLATINUM-BASED DERIVATIVES WITHIN CARBON NANOTUBES: INVESTIGATIONS ON CONTROLLED RELEASE AND IN VIVO BIODISTRIBUTION. ScholarBank@NUS Repository.
Abstract: This dissertation provides a proof-of-concept on MWCNTs capable of entrapping platinum-based derivatives with high drug loading, and selectively releasing them under pathological conditions. Furthermore, MWCNT-assisted delivery could have an impact on tissue distribution, thus probably exerting an improved pharmacological action and attenuating side effects on non-targeted organs in comparison with drugs alone.
URI: http://scholarbank.nus.edu.sg/handle/10635/37624
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