Please use this identifier to cite or link to this item: https://doi.org/10.1016/0020-7292(92)90723-V
Title: Plasminogen activators and inhibitors in normal late pregnancy, postpartum and in the postnatal period
Authors: Koh, C.L.S. 
Viegas, O.A.C. 
Yuen, R. 
Chua, S.E.
Ng, B.L.
Ratnam, S.S. 
Keywords: Plasminogen activator inhibitors
Pregnancy
Tissue plasminogen activator
Urokinase plasminogen activator
Issue Date: 1992
Source: Koh, C.L.S., Viegas, O.A.C., Yuen, R., Chua, S.E., Ng, B.L., Ratnam, S.S. (1992). Plasminogen activators and inhibitors in normal late pregnancy, postpartum and in the postnatal period. International Journal of Gynecology and Obstetrics 38 (1) : 9-18. ScholarBank@NUS Repository. https://doi.org/10.1016/0020-7292(92)90723-V
Abstract: Tissue plasminogen activator ( t-PA), urokinase plasminogen activator (u-PA) and plasminogen activator inhibitors (PAI) are elevated in late pregnancy with t-PA and u-PA remaining so at 6 weeks postnatal. PAI-2 remains at postpartum but was absent by 6 weeks postnatal unlike PAI activity which was absent at postpartum and returned to nonpregnant level at postnatal. The potential fibrinolytic response to stress is much reduced in pregnancy thus increasing the risk of thromboembolism.
Source Title: International Journal of Gynecology and Obstetrics
URI: http://scholarbank.nus.edu.sg/handle/10635/37379
ISSN: 00207292
DOI: 10.1016/0020-7292(92)90723-V
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