Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0029-7844(98)00349-4
Title: Screening for fetal growth restriction: A mathematical model of the effect of time interval and ultrasound error
Authors: Mongelli, M. 
Ek, S. 
Tambyrajia, R.
Issue Date: 1998
Source: Mongelli, M., Ek, S., Tambyrajia, R. (1998). Screening for fetal growth restriction: A mathematical model of the effect of time interval and ultrasound error. Obstetrics and Gynecology 92 (6) : 908-912. ScholarBank@NUS Repository. https://doi.org/10.1016/S0029-7844(98)00349-4
Abstract: Objective: We estimated the effect of ultrasound error and time interval between examinations on the false-positive rate for detecting fetal growth restriction (FGR). Methods: Using published growth curves for the fetal abdominal circumference and a coefficient of variation for ultrasound error of 5%, computer simulation was used to estimate false-positive rates in relation to the time interval between ultrasound examinations. Growth restriction was diagnosed when there was no apparent growth in fetal abdominal circumference between two consecutive examinations. In separate studies, the false-positive rate was plotted against gestational age at the first ultrasound examination. Results: There was a dramatic increase in false-positive rates as the time interval between examinations was reduced. When the initial scan was performed at 32 weeks, the false-positive rate increased from 3.2% for an interval of 4 weeks to 30.8% for an interval of 1 week. At a 2-week interval, the error was 16.9%. There was a significant increase in the false-positive rate as the gestational age at the initial ultrasound was increased. At 28 weeks, the false-positive rate with a 2-week interval was 11.8%, increasing to 24.1% at 38 weeks. By varying the coefficient of variation of the ultrasound error, the false-positive rate increased from 0.8% at an error of 2% to 31.9% at an error of 10%. Conclusion: Ultrasound scanning at 2-week intervals is associated with false- positive rates for growth restriction in excess of 10%, increasing to much higher rates late in the third trimester. Improved screening performance should be attainable by increasing the interval between scans and reducing measurement errors.
Source Title: Obstetrics and Gynecology
URI: http://scholarbank.nus.edu.sg/handle/10635/37163
ISSN: 00297844
DOI: 10.1016/S0029-7844(98)00349-4
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

55
checked on Dec 14, 2017

WEB OF SCIENCETM
Citations

48
checked on Nov 17, 2017

Page view(s)

93
checked on Dec 10, 2017

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.