Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/36140
Title: REGULATION OF RECEPTOR TRAFFICKING IN MAMMALIAN CELLS BY ANDROGRAPHOLIDE
Authors: TAN YINGROU
Keywords: Andrographolide, epidermal growth factor receptor, transferrin receptor, phagocytosis, receptor trafficking
Issue Date: 11-Jun-2012
Source: TAN YINGROU (2012-06-11). REGULATION OF RECEPTOR TRAFFICKING IN MAMMALIAN CELLS BY ANDROGRAPHOLIDE. ScholarBank@NUS Repository.
Abstract: Andrographolide (ADO) is one of the many active components of the traditional herb Andrographis paniculata, which has been extensively used in various forms of Ayruvedic and Chinese Medicine. It is a highly versatile compound and has effects on different systems. The most well-known effect of ADO to date is its anti-inflammatory effect due to its ability to inhibit NF-kB activation, and it has been shown to alleviate the effects of many inflammatory diseases. However, the cellular mechanism of ADO has not yet been fully elucidated, and hence the purpose of this project is to elucidate the mechanism through which ADO exerts its various effects on receptor trafficking and signalling.
URI: http://scholarbank.nus.edu.sg/handle/10635/36140
Appears in Collections:Ph.D Theses (Open)

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