Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/33897
Title: The expression of proteins and activities of metabolic enzymes in transplanted brain tissue
Authors: Leong, S.F. 
Leung, T.K.C. 
Leong, S.K. 
Keywords: allograft
brain protein
development
energy metabolizing enzyme
homotopic transplantation
two-dimensional gel
Issue Date: 1991
Citation: Leong, S.F., Leung, T.K.C., Leong, S.K. (1991). The expression of proteins and activities of metabolic enzymes in transplanted brain tissue. Brain Research 560 (1-2) : 50-54. ScholarBank@NUS Repository.
Abstract: The middle three-fifths of the forebrains of 14-day-old embryos were obtained and transplanted into the cortical cavities of adult rats made 7 days prior to the transplantation. The expression of proteins, as revealed by 2-dimensional gel electrophoresis studies, and the activities of energy metabolizing enzymes in the mature allografts were compared with those in the 14-day-old embryonic forebrains and corresponding areas in the contralateral cerebral hemispheres of the hosts. They were shown to approach adult pattern and adult values after 10-12 weeks of growth. The biochemical findings were discussed and correlated with some of the anatomical observations.
Source Title: Brain Research
URI: http://scholarbank.nus.edu.sg/handle/10635/33897
ISSN: 00068993
Appears in Collections:Staff Publications

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