Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/33368
Title: STUDY ON UV DISINFECTION AND THE EFFECT OF UPSTREAM COAGULATION-MF/UF FILTRATION USING VIRAL SURROGATES.
Authors: GUO HUILING
Keywords: Coagulation, MF/UF Filtration, MS2 Bacteriophage, Surrogates, UV disinfection, virus removal
Issue Date: 19-Dec-2011
Source: GUO HUILING (2011-12-19). STUDY ON UV DISINFECTION AND THE EFFECT OF UPSTREAM COAGULATION-MF/UF FILTRATION USING VIRAL SURROGATES.. ScholarBank@NUS Repository.
Abstract: Viruses are crucial challenge microorganisms to MF/UF and UV disinfection. This is due to the sizes of viruses which are smaller than/comparable to MF/UF membrane pores, and to the higher resistances of viruses (particularly Adenoviruses) to UV disinfection. This study focuses on the removal of viruses via hybrid coagulation-MF/UF filtration followed by UV disinfection. LP and MP UV disinfection was conducted on AD serotypes 5, 40 and 41 using three different host cells (HEK293, PLC/PRF/5, XP17BE). AD enumerated with different cell lines exhibited different LP UV resistance. With MP UV irradiation, this variability was minimized due to the different extents of repair by the host cells. MS2 used as a target microorganism for coagulation-MF/UF-UV process, and AD5 for UV disinfection, was compared with a series of dye surrogates. MS2 conjugated with fluorescent dyes and fluorescent microspheres were observed to be possible surrogates for viruses during MF/UF filtration and UV disinfection.
URI: http://scholarbank.nus.edu.sg/handle/10635/33368
Appears in Collections:Ph.D Theses (Open)

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