Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/32772
Title: Triacylglycerol-deficient fission yeast and its uses
Authors: YANG, HONGYUAN 
Issue Date: 20-Jan-2009
Source: YANG, HONGYUAN (2009-01-20). Triacylglycerol-deficient fission yeast and its uses. ScholarBank@NUS Repository.
Abstract: A fission yeast having non-functional dga1 and plh1 genes, which is incapable of synthesizing triacylglycerols, is disclosed. The fission yeast is susceptible to lipotoxicity including lipoapoptosis, and is useful for screening of compounds that inhibit or prevent lipotoxicity or lipoapoptosis. The fission yeast strain may be transformed to express a mammalian enzyme involved in triacylglycerol synthesis, and therefore is also useful for screening of compounds that inhibit or prevent triacylglycerol synthesis, which activity is conferred by the mammalian enzyme.
URI: http://scholarbank.nus.edu.sg/handle/10635/32772
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
File Description SizeFormatAccess SettingsVersion 
US7479374.PDF449.26 kBAdobe PDF

OPEN

PublishedView/Download

Page view(s)

135
checked on Dec 8, 2017

Download(s)

74
checked on Dec 8, 2017

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.